Synthesis, characterization of ‎2-amino-pyran ‎and derivatives evaluation of the bacterial, ‎antioxidant and anticancer activity

Using ethanol as a solvent, heterocyclic hexagonal rings for 2-amino-pyran derivatives (I33-I40) were produced by reacting mole of chalcones with malononitrile. Physical properties such melting point, colour, and molecular weight spectroscopic measurements the infrared spectrum, [1H-NMR], [13C-NMR] spectrum used to confirm accuracy prepared compounds' compositions. The biological activity various compounds was investigated in two species pathogenic bacteria, one which is Gram-positive, Staphylococcus aureus, other, Gram-negative, Escherichia coli. Chemical solutions substances (I25, I32) concentrations (0,01, 0.001, 0.0001) mg /ml created using solvent DMSO Multer Hinton Agar growth medium. antibiotic Ciprofloxacin utilized control sample diffusion sensitivity test bacterial isolates investigation. DPPH root varied concentrations, impact chemical (I32) on elimination free radicals also investigated. Breast cancer cells taken from Baghdad's Medical City efficiency several chemicals against them.